Publications

9p21.3 Coronary Artery Disease Risk Locus Drives Vascular Smooth Muscle Cells to an Osteochondrogenic State

Salido E., de Medeiros Vieira C., Verdezoto Mosquera J., Zade R., Parikh P., Suryavanshi S., Miller C.L., Lo Sardo V. ., ATVB (2025)

Lo Sardo V., Kamp T. J. Circulation (2022)

High Shear Stress enhances Endothelial Permeability in the presence of the Risk Haplotype at 9p21.3

Teng E. L., Masutani E. M., Yeoman B., Fung J., Lian R., Ngo B., Kumar A., Placone J. K., Lo Sardo V. and Engler A., APL Bioengineering (2021)

Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274

Meckelmann S.W., Hawksworth J.I., White D., Andrews R., Rodrigues P., O'Connor A., Alvarez-Jarreta J., Tyrrell V.J., Hinz C., Zhou Y., Williams J., Aldrovandi M., Watkins W.J., Engler A.J., Lo Sardo V., Slatter D.A., Allen S.T., Acharya J., Mitchell J., Cooper J., Aoki J., Kano K., Humphries S.E., O'Donnell V.B. , Circulation Genomics and Precision Medicine 2020

Mechanical activation of noncoding-RNA-mediated regulation of disease-associated phenotypes in human cardiomyocytes

Kumar A., Thomas S.K., Wong K.C., Lo Sardo V., Cheah D.S., Hou Y., Placone J.K., Tenerelli K.P., Ferguson W., Torkamani A., Topol E.J., Baldwin K.K, Engler A.J., Nature Biomedical Engineering 2018

Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing

Lo Sardo V., Chubukov P., Ferguson W., Kumar A., Teng E.L., Duran M., Zhang L., Cost G., Engler A.J., Urnov F., Topol E.J., Torkamani A., Baldwin K.K., Cell 2018

Influence of donor age on induced pluripotent stem cells

Lo Sardo V., Ferguson W., Erikson G.A., Topol E.J., Baldwin K.K., Torkamani A., Nature Biotechnology 2017

Selective conversion of fibroblasts into peripheral sensory neurons

Blanchard J.W., Eade K.T., Szücs A., Lo Sardo V., Tsunemoto R.K, Williams D., Sanna P.P., Baldwin K.K., Nature Neuroscience 2015

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

Lo Sardo V.*, Zuccato C.*, Gaudenzi G., Vitali B., Ramos C., Tartari M., Myre M., Walker J., Pistocchi A., Conti L., Valenza M., Drung B., Schmidt B., Gusella J., Zeitlin S., Cotelli F. and Cattaneo E., Nature Neuroscience 2012

Phylogenetic comparison of huntingtin homologues reveals the appearance of a primitive polyQ in sea urchin

Tartari M., Gissi C., Lo Sardo V., Pesole G., Cattaneo E., Molecular Biology and Evolution 2008

Heterogeneous Expression of Alternatively Spliced lncRNA mediates Vascular Smooth Cell Plasticity

Mayner J., Masutani E.M., Demeester E., Kumar A., Macapugay G., Beri P., Lo Sardo V. and Engler A., PNAS (2023)